Complete guide to vendor credentialing requirements for Prisma Health facilities. Learn which platform they use, what documentation you need, and how to get credentialed.
Prisma Health is the largest not-for-profit health organization in South Carolina, formed through the merger of Upstate and Midlands health systems. With 18 hospitals and more than 300 care locations, Prisma Health serves more than 1.2 million unique patients annually across the Upstate and Midlands regions of South Carolina.
Prisma Health uses GHX Vendormate for vendor credentialing across its facilities. All vendor representatives must register and maintain active credentials in GHX Vendormate before visiting Prisma Health facilities.
Register on GHX Vendormate →Partner offer
Need a drug screen for credentialing? The test usually is not specific to any one platform or hospital — one comprehensive panel can satisfy the requirement at nearly every facility. Our partner Accesa Labs offers a single chain-of-custody urine test that screens for 19 drugs, including fentanyl and other synthetic opioids, so one order covers you in almost every situation instead of a separate test per credentialing company.
Order the Credentialing Drug Panel → (Partner link — HCH may earn a referral fee.)
Requirements vary by facility. Always verify current requirements on GHX Vendormate before scheduling a visit. Platform confirmed against Prisma Health's own supplier information page (checked 17 August 2026).
Create your vendor representative profile at registersupplier.ghx.com. Include your company affiliation, territory coverage, and product categories.
Upload all required credentialing documents including insurance certificates, background check, drug screen, and HIPAA training.
Prisma Health's compliance team processes applications on a timeline that varies by facility for complete submissions.
Always check in via GHX Vendormate kiosk or app before entering any Prisma Health facility. Keep your vendor badge visible at all times.
Search our database of nearly 18,000 U.S. hospitals, surgery centers and clinics to find specific credentialing requirements for any Prisma Health facility.
Search Hospitals → Browse by State →Enter your email and we’ll send you the PDF. You’ll also join the HCH mailing list — occasional updates on new credentialing platform alignments and major vendor credentialing news. Unsubscribe anytime.
Or read the full 2026 Vendor Credentialing Requirements Guide — everything you need to know about hospital vendor credentialing in 2026.